RNA
Part:BBa_K3824003:Design
Designed by: Woo Rin Lee Group: iGEM21_Korea_HS (2021-09-28)
siRNA targeting CYP1A1
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
CYP1A1 targeting sequence position was considered. siRNA CYP1A1 was designed to degrade CYP1A1 mRNA in cancer cells to increase drug sensitivity of doxorubicin
Source
siRNA was synthesized by Bioneer, a biotech company in Korea